ONCOLOGY

INDIVIDUAL MARKERS – REAL-TIME PCR PANELS

Advanced molecular diagnostics for cancer-associated genetic markers, mutations and therapeutic biomarkers to support precision oncology, treatment selection and personalized patient management.

ONCOLOGY – REAL-TIME PCR PANELS

S. NO.	FOCUS / PANEL	REAL-TIME PCR PANEL	TARGETS / DETECTION	IMPACT OF PANEL	USE OF PANEL	TEST TYPE	LEAD TIME	BOOK APPOINTMENT
1	Acute Leukemia	Acute Leukemia Panel Kit	Comprehensive detection & differentiation of mutations FLT3 NPM1 CEBPA RUNX1 WT1 IKZF1 ETV6 ABL1 JAK2	Enables comprehensive profiling of acute leukemia molecular abnormalities for assessment, risk stratification and disease monitoring.	Diagnosis, prognosis, MRD monitoring and treatment stratification in acute leukemia.	REAL-TIME RT-PCR	48–72 HOURS
2	ALL	ALL Comprehensive Panel Kit	Comprehensive mutation detection BCR-ABL PAX5 IKZF1 JAK2 CRLF2 ETV6 TP53	Helps in accurate diagnosis and classification of ALL with prognostic evaluation and risk assessment.	MRD monitoring, risk assessment and management decisions in ALL patients.	REAL-TIME RT-PCR	48–72 HOURS
3	AML	AML Comprehensive Panel Kit	Comprehensive detection & identification of mutations FLT3 NPM1 CEBPA IDH1 IDH2 DNMT3A RUNX1 TP53 ASXL1	Provides complete molecular landscape for precise AML subtyping and targeted treatment strategies.	Diagnosis, prognosis and selection of targeted therapy in AML.	REAL-TIME RT-PCR	48–72 HOURS
4	Colorectal Cancer	Colorectal Cancer Mutations Panel Kit	Comprehensive detection of mutations in key genes KRAS NRAS BRAF PIK3CA TP53	Helps in identifying appropriate targeted therapy and treatment response assessment.	Therapy selection, prognosis and monitoring of treatment response.	REAL-TIME RT-PCR	48–72 HOURS
5	Glioblastoma	Glioblastoma Mutations Panel Kit	IDH1 IDH2 MGMT TP53 EGFR TERT	Aid in prognosis prediction and identification of molecular alterations for targeted therapy.	Prognosis assessment and guidance for personalized therapy.	REAL-TIME RT-PCR	> 48–72 HOURS
6	Leukemia Fusion	Leukemia Fusion Panel Kit	Comprehensive detection & identification of fusion variants BCR-ABL PML-RARA RUNX1-RUNX1T1 CBFB-MYH11 ETV6-RUNX1	Enables accurate detection of gene fusions for better disease classification.	Diagnosis, MRD monitoring and treatment stratification.	REAL-TIME RT-PCR	48–72 HOURS
7	Lung Cancer	Lung Cancer Mutations Panel Kit	EGFR ALK ROS1 KRAS BRAF MET RET ERBB2	Helps identify actionable mutations for targeted therapy and improved treatment planning.	Patient selection for targeted therapy and response monitoring.	REAL-TIME RT-PCR	48–72 HOURS
8	Melanoma	Melanoma Mutations Panel Kit	BRAF NRAS NF1 TP53 CDKN2A	Supports accurate diagnosis and targeted therapy selection in melanoma.	Therapy selection, prognosis and monitoring of treatment response.	REAL-TIME RT-PCR	48–72 HOURS
9	MPN	MPN Mutations Panel Kit	JAK2 CALR MPL CSF3R ASXL1 TET2 DNMT3A	Enables detection of mutations associated with myeloproliferative neoplasms.	Diagnosis, prognosis and monitoring of MPN patients.	REAL-TIME RT-PCR	48–72 HOURS
10	Pediatric Leukemia	Pediatric Leukemia Panel Kit	Comprehensive detection of pediatric leukemia markers KMT2A RUNX1 ETV6 IKZF1 PAX5 BCR-ABL	Enables precise molecular diagnosis and risk stratification in pediatric leukemia.	Diagnosis, risk stratification, MRD monitoring and treatment.	REAL-TIME RT-PCR	48–72 HOURS

ONCOLOGY – INDIVIDUAL MARKERS – REAL-TIME PCR PANELS

S. NO.	ORGAN / FOCUS	REAL-TIME PCR PANEL	TARGETS / DETECTION	IMPACT OF PANEL	USE OF PANEL	TEST TYPE	LEAD TIME	BOOK APPOINTMENT
1		Panel ALK Fusion	Qualitative detection of ALK gene fusion ALK rearrangements ALK-associated molecular alterations	ALK fusion detection supports molecular characterization of selected cancers and targeted therapy decisions.	Detect ALK alterations to support targeted therapy selection.	REAL-TIME RT-PCR	48–72 HOURS
2		Panel BCR-ABL1 Major	Quantitative detection of BCR-ABL1 Major breakpoint region Real-Time PCR detection	Major BCR-ABL1 transcripts support monitoring of BCR-ABL1-positive disease.	Detection and monitoring of BCR-ABL1 molecular response.	REAL-TIME RT-PCR	48–72 HOURS
3		Panel BCR-ABL1 Minor	BCR-ABL1 minor transcript Qualitative / quantitative detection Real-Time PCR	Supports identification of minor BCR-ABL1 molecular variants.	Differentiation of BCR-ABL1 transcript types for molecular monitoring.	REAL-TIME RT-PCR	48–72 HOURS
4		Panel BCR-ABL1 Major & Minor	BCR-ABL1 Major BCR-ABL1 Minor Fusion transcript detection	Provides comprehensive molecular assessment of BCR-ABL1 transcript variants.	Differentiates p210 and p190-associated molecular transcripts.	REAL-TIME RT-PCR	48–72 HOURS
5		Panel GIT Mutations	KRAS NRAS BRAF PIK3CA Other clinically relevant markers	Identification of mutations associated with tumor biology and therapeutic response.	Molecular classification, treatment selection and patient management.	REAL-TIME RT-PCR	48–72 HOURS
6		Panel BCR-ABL1 p210	BCR-ABL1 p210 Major breakpoint transcript Molecular response monitoring	Supports molecular monitoring of BCR-ABL1-positive hematological malignancies.	Monitoring treatment response and molecular remission.	REAL-TIME RT-PCR	48–72 HOURS
7		Panel BCR-ABL1 p190	BCR-ABL1 p190 Minor breakpoint transcript Fusion transcript detection	Supports molecular detection of p190-associated BCR-ABL1 transcripts.	Molecular characterization and treatment monitoring.	REAL-TIME RT-PCR	48–72 HOURS
8		Panel BCR-ABL1 Major & Minor	Major transcript Minor transcript BCR-ABL1 fusion variants	Comprehensive evaluation of BCR-ABL1 molecular variants.	Molecular monitoring and therapy response assessment.	REAL-TIME RT-PCR	48–72 HOURS
9		Panel BCR-ABL1 Transcript	BCR-ABL1 fusion transcript Qualitative detection Real-Time PCR	Provides molecular information for leukemia-associated fusion transcripts.	Identify BCR-ABL1 variants for molecular characterization.	REAL-TIME RT-PCR	48–72 HOURS
10		Panel BCR-ABL1 p190 / p210	BCR-ABL1 p190 BCR-ABL1 p210 Major & minor transcripts	Enables differentiation of BCR-ABL1 transcript variants for disease classification.	Quantitative BCR-ABL1 monitoring for treatment response.	REAL-TIME RT-PCR	48–72 HOURS
11		Panel BCR-ABL1 Screening	BCR-ABL1 fusion Major and minor variants Screening markers	Screening for molecular alterations associated with BCR-ABL1-positive disease.	Comprehensive molecular screening and disease characterization.	REAL-TIME RT-PCR	48–72 HOURS
12		Panel BRAF Mutations	BRAF mutation detection Clinically relevant BRAF variants Real-Time PCR	BRAF mutations may provide important information for molecular characterization and treatment planning.	Detection of BRAF variants to support personalized treatment strategies.	REAL-TIME RT-PCR	48–72 HOURS

S. NO.	ORGAN / FOCUS	MARKER	REAL-TIME PCR KIT	TARGETS / DETECTION	IMPACT	USE OF PANEL	TEST TYPE	LEAD TIME	BOOK APPOINTMENT
1		C-KIT	Panel C-KIT Mutation Detection	Qualitative detection of C-KIT mutations Detection of clinically relevant C-KIT variants Real-Time PCR	Identifies C-KIT mutations associated with mast cell disorders and supports molecular diagnosis and therapy.	Detect C-KIT mutation to guide targeted therapy and treatment response monitoring.	REAL-TIME PCR	48–72 HOURS
2		CALR	Panel CALR Mutations Detection	Qualitative detection and differentiation Type 1 & Type 2 CALR mutations Real-Time PCR	Essential for diagnosis and classification of MPNs and molecular clonality monitoring.	Detect CALR Type 1 and Type 2 mutations for diagnosis and prognosis.	REAL-TIME PCR	48–72 HOURS
3		CXCR4	Panel CXCR4 Mutations Detection Panel	Qualitative detection of CXCR4 S338X CXCR4 mutations Real-Time PCR	Helps in prognosis and risk stratification in hematologic malignancies and stem cell mobilization.	Detect CXCR4 S338X mutation for clinical decision making.	REAL-TIME PCR	48–72 HOURS
4		EGFR	Panel EGFR Mutations Detection Panel	Qualitative detection of EGFR mutations Exons 18, 19, 20 & 21 Real-Time PCR	Enables precise NSCLC subtyping for targeted therapy and improved patient outcomes.	Detect EGFR mutations to guide TKI therapy selection and monitor resistance.	REAL-TIME PCR	48–72 HOURS
5		FLT3	Panel FLT3 Mutations Detection	Qualitative detection of FLT3 mutations ITD (D835, 836) TKD mutations	Important for risk stratification in AML and treatment decision support.	Detect FLT3 ITD/TKD mutations for prognosis and therapy planning.	REAL-TIME PCR	48–72 HOURS
6		IDH 1/2	Panel IDH1/2 Mutations Detection	Qualitative detection of IDH1 IDH2 mutations Somatic mutation detection	Crucial for classification of glioma and AML with prognostic significance.	Detect IDH1/2 mutations for accurate diagnosis and prognosis.	REAL-TIME PCR	48–72 HOURS
7		IDH 1/2	Panel IDH1/2 Detection & Differentiation	Qualitative detection IDH1 & IDH2 somatic mutations Mutation differentiation	Differentiates IDH1 from IDH2 mutations for precise molecular characterization.	Differentiated detection to guide prognosis and treatment strategy.	REAL-TIME PCR	48–72 HOURS
8		JAK2	Panel JAK2 Mutations Detection	Qualitative detection of JAK2 V617F mutation Real-Time PCR	Key marker for MPNs diagnosis and clonal evolution monitoring.	Detect JAK2 V617F mutation for diagnosis and monitoring.	REAL-TIME PCR	48–72 HOURS
9		JAK2 QT	Panel JAK2 QT Kit (Allele Burden)	Quantitative detection JAK2 V617F mutation Allele burden measurement	Quantifies allele burden to assess disease status and response to therapy.	Monitor JAK2 allele burden for treatment response and prognosis.	REAL-TIME PCR	48–72 HOURS
10		KRAS	Panel KRAS Mutations Detection Panel	Qualitative detection KRAS codons 12, 13, 59, 61 117 & 146	Essential for colorectal cancer therapy selection and anti-EGFR therapy decisions.	Detect KRAS mutations to guide therapy and predict treatment response.	REAL-TIME PCR	48–72 HOURS
11		MGMT	Panel MGMT Methylation Detection Panel	Qualitative detection Promoter methylation MGMT gene	Predicts response to temozolomide therapy in glioblastoma patients.	Assess MGMT promoter methylation for therapy response prediction.	REAL-TIME PCR	48–72 HOURS
12		MPL	Panel MPL Mutations Detection	Qualitative detection W515K W515L & W515S	Important for MPN diagnosis, prognosis and treatment monitoring.	Detect MPL mutations for risk stratification and clinical management.	REAL-TIME PCR	48–72 HOURS

ONCOLOGY – INDIVIDUAL MARKERS – REAL-TIME PCR KITS

S. NO.	ORGAN / FOCUS	MARKER	PANEL	DETECTION / TARGET	IMPACT	USE OF PANEL	TEST TYPE	LEAD TIME	BOOK APPOINTMENT
1		MYD88	MYD88 Mutations Detection Panel	Qualitative detection of L265P mutation in the MYD88 gene Real-Time PCR	Identification of MYD88 mutation associated with lymphoplasmacytic lymphoma.	Detect MYD88 mutation to aid diagnosis and guide appropriate therapy.	REAL-TIME PCR	48–72 HOURS
2		NPM1	NPM1 Mutations Detection Panel	Qualitative detection & differentiation Type A & other NPM1 mutations Real-Time PCR	Essential for AML diagnosis, prognosis and minimal residual disease monitoring.	Detect NPM1 mutations for risk stratification and treatment decision support.	REAL-TIME PCR	48–72 HOURS
3		NPM1 QT	NPM1 Mutations Quantitative Panel	Detection, differentiation & quantification NPM1 mutation burden Real-Time PCR	Quantifies NPM1 mutation allele burden for therapy response monitoring.	Monitor treatment response and MRD for better clinical management.	REAL-TIME PCR	48–72 HOURS
4		NRAS	NRAS Mutations Detection Panel	Qualitative detection of NRAS mutations Codons 12, 13, 59, 61, 117 & 146 Real-Time PCR	Helps in prognosis & treatment response for targeted therapy.	Detect NRAS mutations to guide targeted therapy selection & disease monitoring.	REAL-TIME PCR	48–72 HOURS
5		NUP214 (CAN)	NUP214 (CAN) Rearrangements Panel	Qualitative detection of DDXC8-NUP214 SET-NUP214 transcripts Real-Time PCR	Important for accurate diagnosis and classification of hematological malignancies.	Detect NUP214 rearrangements for risk stratification and therapy decisions.	REAL-TIME PCR	48–72 HOURS
6		PIK3CA	PIK3CA Mutations Detection Panel	Qualitative detection of PIK3CA mutations Common PIK3CA mutations Real-Time PCR	Plays a key role in cancer development & response to PI3K inhibitor therapy.	Detect PIK3CA mutations to guide targeted therapies and improve prognosis.	REAL-TIME PCR	48–72 HOURS
7		PML-RARA QL	PML-RARA Qualitative Detection Panel	Qualitative detection of BCR1, BCR2 & BCR3 PML-RARA transcripts Real-Time PCR	Critical for early & accurate diagnosis of Acute Promyelocytic Leukemia (APL).	Detect PML-RARA transcripts for diagnosis & therapy stratification.	REAL-TIME PCR	48–72 HOURS
8		PML-RARA QT	PML-RARA Quantitative PCR Panel	Detection & quantification BCR1, BCR2 & BCR3 transcripts Real-Time PCR	Enables MRD monitoring and quantitative assessment for treatment response.	Monitor treatment response, MRD & relapse in APL patients.	REAL-TIME PCR	48–72 HOURS
9		RBM15- MKL1	RBM15-MKL1 Fusion Detection Panel	Qualitative detection of RBM15-MKL1 fusion t(1;22) translocation Real-Time PCR	Aids in diagnosis & classification of acute megakaryoblastic leukemia.	Detect RBM15-MKL1 fusion for accurate diagnosis & risk assessment.	REAL-TIME PCR	48–72 HOURS
10		ROS1	ROS1 Fusion Detection Panel	Qualitative detection of ROS1 fusion transcripts Real-Time PCR	Helps identify ROS1 rearrangements in lung and other solid tumors.	Detect ROS1 fusion for targeted therapy eligibility and improved outcomes.	REAL-TIME PCR	48–72 HOURS