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PHARMACOGENOMICS (PGx)

INDIVIDUAL MARKERS – REAL-TIME PCR PANELS

Precision Medicine. Better Outcomes.

Molecular insights for personalized drug therapy, improved safety, optimized treatment decisions and better patient outcomes through pharmacogenomic marker analysis.

PHARMACOGENOMICS (PGx) – REAL-TIME PCR PANELS
S.NO. ORGAN /
FOCUS 		MARKER PANEL DETECTION / TARGET IMPACT USE OF PANEL LEAD TIME BOOK
APPOINTMENT
1
Respiratory Infections > DPYD DPYD Mutations
Detection
Panel
  • Qualitative detection of 4 clinically relevant SNPs in the DPYD gene:
  • c.1905+1G>A
  • c.1679T>G
  • c.2846A>T
  • c.1236G>A
  • Real-Time PCR
  • Identifies risk of severe toxicity to fluoropyrimidines (5-FU, capecitabine).
  • Helps in dose individualization to reduce adverse drug reactions.
  • Improves patient safety & treatment outcomes.
  • Guides safe & effective use of fluoropyrimidine chemotherapy.
  • Supports personalized dose adjustments based on DPYD genetic status.
◷
48–72
HOURS
2
Respiratory Infections TPMT TPMT Mutations
Detection
Panel
  • Qualitative detection of 4 clinically relevant SNPs in the TPMT gene:
  • c.238G>C
  • c.460A>G
  • c.719A>G
  • c.626-6T>G
  • Real-Time PCR
  • Detects TPMT variants associated with myelosuppression & drug intolerance.
  • Enables safer thiopurine therapy in high-risk patients.
  • Supports therapeutic response & reduced treatment-related toxicity.
  • Guides dosing decisions for thiopurine therapies in oncology & immunosuppressive treatment.
  • Supports precision medicine & improved patient safety.
◷
48–72
HOURS
3
Respiratory Infections MTHFR MTHFR Mutations
Detection
Panel
  • Qualitative detection of clinically relevant SNPs in the MTHFR gene:
  • c.677C>T (C677T)
  • c.1298A>C (A1298C)
  • Real-Time PCR
  • Identifies genetic risk for hyperhomocysteinemia.
  • Helps in folate metabolism assessment & related health risks.
  • Supports therapy optimization & prevention strategies.
  • Useful in cardiovascular & neurological risk assessment.
  • Helps guide folate supplementation & management plans.
◷
48–72
HOURS

PERSONALIZED THERAPY

Molecular insights support individualized treatment decisions and personalized drug therapy.

REDUCED ADVERSE REACTIONS

Pharmacogenomic testing can help identify genetic factors associated with treatment-related toxicity.

OPTIMIZED TREATMENT

Supports appropriate therapy, dose optimization and evidence-based clinical decision making.

PRECISION MEDICINE

Genetic information can contribute to safer, more effective and personalized healthcare.